At just the age of 9, he starts playing and studying the organ, mainly dedicated to the contamination of various styles and harmonies of the instrument, which were not popular at the time. He is a solo organist and the artistic coordinator of the “Orchestra Bottoni”. D’Alessandro was also co-producer and arranger of the “Omaggio a N.Orleans” (2006) of POLV & Blue Stuff, “The Journey” (2011) by Dan Moretti & POLV and ” Orchestra Bottoni Live “(2014, finalist of the Tenco Prize, and second at the Premio Loano 2014).He maintains a stable musical career, working on projects for artists such as: Canio Loguercio, Rocco De Rosa, Nando Citarella, Badara Seck, Roberto Billi, etc. He also collaborates both in the studio, and on stage with Maria Pia De Vito, Lucilla Galeazzi, Badara Seck, Nando Citarella & Tamburi del Vesuvio, Michele Rabbia, Daniele Sepe & RJF, Stefano Saletti & Piccola Banda Ikona, Riccardo Tesi & Banditaliana, Flo, Zibba & Almalibre, Giuseppe “Spedino” Moffa, Carmine Ioanna, Andrea Satta (Tetes de Bois), Rom & Gagè, Mauro Palmas, Zampognòrchestra, Unavantaluna, Ettore Fioravanti, Eugenio Colombo, Massimo Carrano, Mohssen Kasirossafar, Giuliana De Donno, Michele Santoro , Giovanni Truppi, Nu Indaco, Paolo Modugno, Gang, Blue Stuff, Band “Isola del Liri”, Costanza Alegiani, Pasquale Innarella, Arnaldo Vacca, Takadum Orchèstra …
Alessandro D’Alessandro worked in theatre and literature with Eugenio Barba & Odin Teatret, Teatro Potlach, Sonia Bergamasco, Franco Arminio, Gaspare Balsamo, Maria Grazia Calandrone, Marcello Sambati, Marcello Tagliente, Andrea Cosentino, Gilda Policastro, Lidia Riviello, Recital Project, Production Poor , Bartolini-Baronio Company, etc.